transcriptome-wide

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    RNA G-Quadruplex Structures Mediate Gene Regulation in Bacteria
    Research Article | Molecular Biology and Physiology
    RNA G-Quadruplex Structures Mediate Gene Regulation in Bacteria

    G-quadruplex in RNA (rG4) mediates various biological functions and cellular processes in eukaryotic organisms. However, the presence, locations, and functions of rG4 are still elusive in prokaryotes. Here, we found that rG4 is an abundant RNA secondary structure across a wide range of bacterial species. Subsequently, the transcriptome-wide rG4 structure sequencing (rG4-seq) revealed that the model...

    Xiaolong Shao, Weitong Zhang, Mubarak Ishaq Umar, Hei Yuen Wong, Zijing Seng, Yingpeng Xie, Yingchao Zhang, Liang Yang, Chun Kit Kwok, Xin Deng
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