Skip to main content
  • ASM
    • Antimicrobial Agents and Chemotherapy
    • Applied and Environmental Microbiology
    • Clinical Microbiology Reviews
    • Clinical and Vaccine Immunology
    • EcoSal Plus
    • Eukaryotic Cell
    • Infection and Immunity
    • Journal of Bacteriology
    • Journal of Clinical Microbiology
    • Journal of Microbiology & Biology Education
    • Journal of Virology
    • mBio
    • Microbiology and Molecular Biology Reviews
    • Microbiology Resource Announcements
    • Microbiology Spectrum
    • Molecular and Cellular Biology
    • mSphere
    • mSystems
  • Log in
  • My alerts
  • My Cart

Main menu

  • Home
  • Articles
    • Latest Articles
    • COVID-19 Special Collection
    • Archive
    • Minireviews
  • Topics
    • Applied and Environmental Science
    • Clinical Science and Epidemiology
    • Ecological and Evolutionary Science
    • Host-Microbe Biology
    • Molecular Biology and Physiology
    • Therapeutics and Prevention
  • For Authors
    • Submit a Manuscript
    • Scope
    • Editorial Policy
    • Submission, Review, & Publication Processes
    • Organization and Format
    • Errata, Author Corrections, Retractions
    • Illustrations and Tables
    • Nomenclature
    • Abbreviations and Conventions
    • Publication Fees
    • Ethics Resources and Policies
  • About the Journal
    • About mBio
    • Editor in Chief
    • Board of Editors
    • AAM Fellows
    • For Reviewers
    • For the Media
    • For Librarians
    • For Advertisers
    • Alerts
    • RSS
    • FAQ
  • ASM
    • Antimicrobial Agents and Chemotherapy
    • Applied and Environmental Microbiology
    • Clinical Microbiology Reviews
    • Clinical and Vaccine Immunology
    • EcoSal Plus
    • Eukaryotic Cell
    • Infection and Immunity
    • Journal of Bacteriology
    • Journal of Clinical Microbiology
    • Journal of Microbiology & Biology Education
    • Journal of Virology
    • mBio
    • Microbiology and Molecular Biology Reviews
    • Microbiology Resource Announcements
    • Microbiology Spectrum
    • Molecular and Cellular Biology
    • mSphere
    • mSystems

User menu

  • Log in
  • My alerts
  • My Cart

Search

  • Advanced search
mBio
publisher-logosite-logo

Advanced Search

  • Home
  • Articles
    • Latest Articles
    • COVID-19 Special Collection
    • Archive
    • Minireviews
  • Topics
    • Applied and Environmental Science
    • Clinical Science and Epidemiology
    • Ecological and Evolutionary Science
    • Host-Microbe Biology
    • Molecular Biology and Physiology
    • Therapeutics and Prevention
  • For Authors
    • Submit a Manuscript
    • Scope
    • Editorial Policy
    • Submission, Review, & Publication Processes
    • Organization and Format
    • Errata, Author Corrections, Retractions
    • Illustrations and Tables
    • Nomenclature
    • Abbreviations and Conventions
    • Publication Fees
    • Ethics Resources and Policies
  • About the Journal
    • About mBio
    • Editor in Chief
    • Board of Editors
    • AAM Fellows
    • For Reviewers
    • For the Media
    • For Librarians
    • For Advertisers
    • Alerts
    • RSS
    • FAQ

transcriptional regulation

  • Open Access
    Subcellular Architecture of the <em>xyl</em> Gene Expression Flow of the TOL Catabolic Plasmid of <span class="named-content genus-species" id="named-content-1">Pseudomonas putida</span> mt-2
    Editor's Pick Research Article | Molecular Biology and Physiology
    Subcellular Architecture of the xyl Gene Expression Flow of the TOL Catabolic Plasmid of Pseudomonas putida mt-2

    The transfer of information between DNA, RNA, and proteins in a bacterium is often compared to the decoding of a piece of software in a computer. However, the tridimensional layout and the relational logic of the cognate biological hardware, i.e., the nucleoid, the RNA polymerase, and the ribosomes, are habitually taken for granted.

    Juhyun Kim, Angel Goñi-Moreno, Víctor de Lorenzo
  • Open Access
    A Novel <span class="named-content genus-species" id="named-content-1">Enterococcus faecalis</span> Heme Transport Regulator (FhtR) Senses Host Heme To Control Its Intracellular Homeostasis
    Research Article | Host-Microbe Biology
    A Novel Enterococcus faecalis Heme Transport Regulator (FhtR) Senses Host Heme To Control Its Intracellular Homeostasis

    Enterococcus faecalis, a normal and harmless colonizer of the human intestinal flora can cause severe infectious diseases in immunocompromised patients, particularly those that have been heavily treated with antibiotics. Therefore, it is important to understand the factors that promote its resistance and its virulence....

    Vincent Saillant, Damien Lipuma, Emeline Ostyn, Laetitia Joubert, Alain Boussac, Hugo Guerin, Géraldine Brandelet, Pascal Arnoux, Delphine Lechardeur
  • Open Access
    Transcriptional Silencing by TsrA in the Evolution of Pathogenic <span class="named-content genus-species" id="named-content-1">Vibrio cholerae</span> Biotypes
    Research Article | Molecular Biology and Physiology
    Transcriptional Silencing by TsrA in the Evolution of Pathogenic Vibrio cholerae Biotypes

    Pathogenic Vibrio cholerae strains express multiple virulence factors that are encoded by bacteriophage and chromosomal islands. These include cholera toxin and the intestinal colonization pilus called the toxin-coregulated pilus, which are essential for causing severe disease in humans. However, it is presently unclear how the expression of these horizontally...

    Florence Caro, José A. Caro, Nicole M. Place, John J. Mekalanos
  • Open Access
    Invertases in <span class="named-content genus-species" id="named-content-1">Phytophthora infestans</span> Localize to Haustoria and Are Programmed for Infection-Specific Expression
    Research Article | Host-Microbe Biology
    Invertases in Phytophthora infestans Localize to Haustoria and Are Programmed for Infection-Specific Expression

    Oomycetes cause hundreds of diseases in economically and environmentally significant plants. How these microbes acquire host nutrients is not well understood. Many oomycetes insert specialized hyphae called haustoria into plant cells, but unlike their fungal counterparts, a role in nutrition has remained unproven. The discovery that Phytophthora invertases localize to haustoria provides the first strong evidence that these...

    Meenakshi S. Kagda, Domingo Martínez-Soto, Audrey M. V. Ah-Fong, Howard S. Judelson
  • Open Access
    Identification of a Novel LysR-Type Transcriptional Regulator in <span class="named-content genus-species" id="named-content-1">Staphylococcus aureus</span> That Is Crucial for Secondary Tissue Colonization during Metastatic Bloodstream Infection
    Research Article | Host-Microbe Biology
    Identification of a Novel LysR-Type Transcriptional Regulator in Staphylococcus aureus That Is Crucial for Secondary Tissue Colonization during Metastatic Bloodstream Infection

    Staphylococcus aureus is an important pathogen that can disseminate via the bloodstream and establish metastatic infections in distant organs. To achieve a better understanding of the bacterial factors facilitating the development of these metastatic infections, we used in this study a Staphylococcus...

    Michaela Groma, Sarah A. Horst, Sudip Das, Bruno Huettel, Maximilian Klepsch, Thomas Rudel, Eva Medina, Martin Fraunholz
  • Open Access
    Translational Regulation Promotes Oxidative Stress Resistance in the Human Fungal Pathogen <span class="named-content genus-species" id="named-content-1">Cryptococcus neoformans</span>
    Research Article | Host-Microbe Biology
    Translational Regulation Promotes Oxidative Stress Resistance in the Human Fungal Pathogen Cryptococcus neoformans

    Fungal survival in a mammalian host requires the coordinated expression and downregulation of a large cohort of genes in response to cellular stresses. Initial infection with C. neoformans occurs in the lungs, where it interacts with host macrophages. Surviving macrophage-derived cellular stresses, such as the production of reactive oxygen and nitrogen species, is...

    Jay Leipheimer, Amanda L. M. Bloom, Christopher S. Campomizzi, Yana Salei, John C. Panepinto
  • Open Access
    The TK0271 Protein Activates Transcription of Aromatic Amino Acid Biosynthesis Genes in the Hyperthermophilic Archaeon <span class="named-content genus-species" id="named-content-1">Thermococcus kodakarensis</span>
    Research Article | Molecular Biology and Physiology
    The TK0271 Protein Activates Transcription of Aromatic Amino Acid Biosynthesis Genes in the Hyperthermophilic Archaeon Thermococcus kodakarensis

    The mechanisms of transcriptional regulation in archaea are still poorly understood. In this study, we identified a transcriptional regulator in the hyperthermophilic archaeon Thermococcus kodakarensis that activates the transcription of three operons involved in the biosynthesis of aromatic amino acids. The study represents one of only a few that identifies a...

    Yasuyuki Yamamoto, Tamotsu Kanai, Tsuyoshi Kaneseki, Haruyuki Atomi
  • Open Access
    Interaction of the Ankyrin H Core Effector of <em>Legionella</em> with the Host LARP7 Component of the 7SK snRNP Complex
    Research Article | Host-Microbe Biology
    Interaction of the Ankyrin H Core Effector of Legionella with the Host LARP7 Component of the 7SK snRNP Complex

    For intracellular pathogens to thrive in host cells, an environment that supports survival and replication needs to be established. L. pneumophila accomplishes this through the activity of the ∼330 effector proteins that are injected into host cells during infection. Effector functions range from hijacking host trafficking pathways to altering host cell machinery,...

    Juanita Von Dwingelo, Ivy Yeuk Wah Chung, Christopher T. Price, Lei Li, Snake Jones, Miroslaw Cygler, Yousef Abu Kwaik
  • Open Access
    Could Dampening Expression of the <span class="named-content genus-species" id="named-content-1">Neisseria gonorrhoeae</span> <em>mtrCDE</em>-Encoded Efflux Pump Be a Strategy To Preserve Currently or Resurrect Formerly Used Antibiotics To Treat Gonorrhea?
    Research Article | Therapeutics and Prevention
    Could Dampening Expression of the Neisseria gonorrhoeae mtrCDE-Encoded Efflux Pump Be a Strategy To Preserve Currently or Resurrect Formerly Used Antibiotics To Treat Gonorrhea?

    The emergence of gonococcal strains resistant to past or currently used antibiotics is a global public health concern, given the estimated 78 million infections that occur annually. The dearth of new antibiotics to treat gonorrhea demands that alternative curative strategies be considered to counteract antibiotic resistance expressed by gonococci. Herein, we show that decreased expression of a drug efflux pump that participates in...

    Shaochun Chen, Kristie L. Connolly, Corinne Rouquette-Loughlin, Alexander D’Andrea, Ann E. Jerse, William M. Shafer
  • Open Access
    A Central Small RNA Regulatory Circuit Controlling Bacterial Denitrification and N<sub>2</sub>O Emissions
    Research Article | Applied and Environmental Science
    A Central Small RNA Regulatory Circuit Controlling Bacterial Denitrification and N2O Emissions

    N2O is an important greenhouse gas and a major cause of ozone depletion. Denitrifying bacteria play vital roles in the production and consumption of N2O in many environments. Complete denitrification consists of the conversion of a soluble N-oxyanion, nitrate (NO3-), to an inert gaseous N-oxide, dinitrogen (N2). Incomplete denitrification can occur if conditions are prohibitive, for...

    Hannah Gaimster, Claire L. Hews, Ryan Griffiths, Manuel J. Soriano-Laguna, Mark Alston, David J. Richardson, Andrew J. Gates, Gary Rowley

Pages

  • Next
  • 1
  • 2
  • 3
Back to top

About

  • About mBio
  • Editor in Chief
  • Board of Editors
  • AAM Fellows
  • Policies
  • For Reviewers
  • For the Media
  • For Librarians
  • For Advertisers
  • Alerts
  • RSS
  • FAQ
  • Permissions
  • Journal Announcements

Authors

  • ASM Author Center
  • Submit a Manuscript
  • Author Warranty
  • Article Types
  • Ethics
  • Contact Us

Follow #mBio

@ASMicrobiology

       

ASM Journals

ASM journals are the most prominent publications in the field, delivering up-to-date and authoritative coverage of both basic and clinical microbiology.

About ASM | Contact Us | Press Room

 

ASM is a member of

Scientific Society Publisher Alliance

 

American Society for Microbiology
1752 N St. NW
Washington, DC 20036
Phone: (202) 737-3600

Copyright © 2021 American Society for Microbiology | Privacy Policy | Website feedback

Online ISSN: 2150-7511