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structural modeling

  • Open Access
    Transcriptional Silencing by TsrA in the Evolution of Pathogenic <span class="named-content genus-species" id="named-content-1">Vibrio cholerae</span> Biotypes
    Research Article | Molecular Biology and Physiology
    Transcriptional Silencing by TsrA in the Evolution of Pathogenic Vibrio cholerae Biotypes

    Pathogenic Vibrio cholerae strains express multiple virulence factors that are encoded by bacteriophage and chromosomal islands. These include cholera toxin and the intestinal colonization pilus called the toxin-coregulated pilus, which are essential for causing severe disease in humans. However, it is presently unclear how the expression of these horizontally...

    Florence Caro, José A. Caro, Nicole M. Place, John J. Mekalanos
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