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phagocytosis

  • Open Access
    Trogocytosis by <span class="named-content genus-species" id="named-content-1">Entamoeba histolytica</span> Mediates Acquisition and Display of Human Cell Membrane Proteins and Evasion of Lysis by Human Serum
    Research Article | Host-Microbe Biology
    Trogocytosis by Entamoeba histolytica Mediates Acquisition and Display of Human Cell Membrane Proteins and Evasion of Lysis by Human Serum

    Entamoeba histolytica causes amoebiasis, a potentially fatal diarrheal disease. Abscesses in organs such as the liver can occur when amoebae are able to breach the intestinal wall and travel through the bloodstream to other areas of the body. Therefore, understanding how E. histolytica evades immune...

    Hannah W. Miller, Rene L. Suleiman, Katherine S. Ralston
  • Open Access
    Editor's Pick Research Article | Host-Microbe Biology
    Candida albicans Hyphal Expansion Causes Phagosomal Membrane Damage and Luminal Alkalinization

    C. albicans is the most common cause of nosocomial fungal infection, and over 3 million people acquire life-threatening invasive fungal infections every year. Even if antifungal drugs exist, almost half of these patients will die. Despite this, fungi remain underestimated as pathogens. Our study uses quantitative biophysical approaches to demonstrate that yeast-to-...

    Johannes Westman, Gary Moran, Selene Mogavero, Bernhard Hube, Sergio Grinstein
  • Open Access
    Editor's Pick Research Article
    Staphylococcus aureus Uses the GraXRS Regulatory System To Sense and Adapt to the Acidified Phagolysosome in Macrophages
    Ronald S. Flannagan, Robert C. Kuiack, Martin J. McGavin, David E. Heinrichs
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