nontuberculous mycobacteria

  • Open Access
    Nrf2 Regulates Granuloma Formation and Macrophage Activation during <span class="named-content genus-species" id="named-content-1">Mycobacterium avium</span> Infection via Mediating Nramp1 and HO-1 Expressions
    Research Article | Host-Microbe Biology
    Nrf2 Regulates Granuloma Formation and Macrophage Activation during Mycobacterium avium Infection via Mediating Nramp1 and HO-1 Expressions

    Nontuberculous mycobacteria (NTM) are an important cause of morbidity and mortality in pulmonary infections. Among them, Mycobacterium avium complex (MAC) is the most common cause of pulmonary NTM disease worldwide.

    Masayuki Nakajima, Masashi Matsuyama, Mio Kawaguchi, Takumi Kiwamoto, Yosuke Matsuno, Yuko Morishima, Kazufumi Yoshida, Mingma Sherpa, Kai Yazaki, Hajime Osawa, Masafumi Muratani, Yukio Ishii, Nobuyuki Hizawa
  • Open Access
    Novel Antimicrobials from Uncultured Bacteria Acting against <span class="named-content genus-species" id="named-content-1">Mycobacterium tuberculosis</span>
    Research Article | Therapeutics and Prevention
    Novel Antimicrobials from Uncultured Bacteria Acting against Mycobacterium tuberculosis

    Decreasing discovery rates and increasing resistance have underscored the need for novel therapeutic options to treat Mycobacterium tuberculosis infection. Here, we screen extracts from previously uncultured soil microbes for specific activity against Mycobacterium tuberculosis, identifying three...

    Jeffrey Quigley, Aaron Peoples, Asel Sarybaeva, Dallas Hughes, Meghan Ghiglieri, Catherine Achorn, Alysha Desrosiers, Cintia Felix, Libang Liang, Stephanie Malveira, William Millett, Anthony Nitti, Baldwin Tran, Ashley Zullo, Clemens Anklin, Amy Spoering, Losee Lucy Ling, Kim Lewis
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