multiomics

  • Open Access
    Tiny Earth: A Big Idea for STEM Education and Antibiotic Discovery
    Observation | Therapeutics and Prevention
    Tiny Earth: A Big Idea for STEM Education and Antibiotic Discovery

    The world faces two seemingly unrelated challenges—a shortfall in the STEM workforce and increasing antibiotic resistance among bacterial pathogens. We address these two challenges with Tiny Earth, an undergraduate research course that excites students about science and creates a pipeline for antibiotic discovery.

    Amanda Hurley, Marc G. Chevrette, Deepa D. Acharya, Gabriel L. Lozano, Manuel Garavito, Jen Heinritz, Luis Balderrama, Mara Beebe, Martel L. DenHartog, Kamiyah Corinaldi, Renee Engels, Alyssa Gutierrez, Orli Jona, Josephine H. I. Putnam, Brody Rhodes, Tiffany Tsang, Simon Hernandez, Carol Bascom-Slack, Jessamina E. Blum, Paul A. Price, Debra Davis, Joanna Klein, Joshua Pultorak, Nora L. Sullivan, Nigel J. Mouncey, Pieter C. Dorrestein, Sarah Miller, Nichole A. Broderick, Jo Handelsman
  • Open Access
    Research Article
    Impact of Dietary Resistant Starch on the Human Gut Microbiome, Metaproteome, and Metabolome

    This work was undertaken to obtain a mechanistic understanding of the complex interplay between diet and the microorganisms residing in the intestine. Although it is known that gut microbes play a key role in digestion of the food that we consume, the specific contributions of different microorganisms are not well understood. In addition, the metabolic pathways and resultant products of metabolism during digestion are highly complex. To...

    Tanja V. Maier, Marianna Lucio, Lang Ho Lee, Nathan C. VerBerkmoes, Colin J. Brislawn, Jörg Bernhardt, Regina Lamendella, Jason E. McDermott, Nathalie Bergeron, Silke S. Heinzmann, James T. Morton, Antonio González, Gail Ackermann, Rob Knight, Katharina Riedel, Ronald M. Krauss, Philippe Schmitt-Kopplin, Janet K. Jansson
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