MDR clonality
- Research Article | Therapeutics and PreventionClonal Confinement of a Highly Mobile Resistance Element Driven by Combination Therapy in Rhodococcus equi
MDR clades arise upon acquisition of resistance traits, but the determinants of their clonal expansion remain largely undefined. Taking advantage of the unique features of Rhodococcus equi infection control in equine farms, involving the same dual antibiotic treatment since the 1980s (a macrolide and rifampin), this study sheds light into the determinants of...