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EptA

  • Open Access
    Dissecting Colistin Resistance Mechanisms in Extensively Drug-Resistant <span class="named-content genus-species" id="named-content-1">Acinetobacter baumannii</span> Clinical Isolates
    Research Article | Therapeutics and Prevention
    Dissecting Colistin Resistance Mechanisms in Extensively Drug-Resistant Acinetobacter baumannii Clinical Isolates

    The discovery of antibiotics revolutionized modern medicine and enabled us to cure previously deadly bacterial infections. However, a progressive increase in antibiotic resistance rates is a major and global threat for our health care system. Colistin represents one of our last-resort antibiotics that is still active against most Gram-negative bacterial pathogens, but increasing resistance is reported worldwide, in particular due to the...

    Vincent Trebosc, Sarah Gartenmann, Marcus Tötzl, Valentina Lucchini, Birgit Schellhorn, Michel Pieren, Sergio Lociuro, Marc Gitzinger, Marcel Tigges, Dirk Bumann, Christian Kemmer
  • Open Access
    Research Article
    An Evolutionarily Conserved Mechanism for Intrinsic and Transferable Polymyxin Resistance
    Yongchang Xu, Wenhui Wei, Sheng Lei, Jingxia Lin, Swaminath Srinivas, Youjun Feng
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