cryptococcosis

  • Open Access
    The Monothiol Glutaredoxin Grx4 Regulates Iron Homeostasis and Virulence in <span class="named-content genus-species" id="named-content-1">Cryptococcus neoformans</span>
    Research Article | Host-Microbe Biology
    The Monothiol Glutaredoxin Grx4 Regulates Iron Homeostasis and Virulence in Cryptococcus neoformans

    Fungal pathogens cause life-threatening diseases in humans, particularly in immunocompromised people, and there is a tremendous need for a greater understanding of pathogenesis to support new therapies. One prominent fungal pathogen, Cryptococcus neoformans, causes meningitis in people suffering from HIV/AIDS. In the present study, we focused on characterizing...

    Rodgoun Attarian, Guanggan Hu, Eddy Sánchez-León, Mélissa Caza, Daniel Croll, Eunsoo Do, Horacio Bach, Tricia Missall, Jennifer Lodge, Won Hee Jung, James W. Kronstad
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