cobalt

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    A Small-Molecule Modulator of Metal Homeostasis in Gram-Positive Pathogens
    Research Article | Host-Microbe Biology
    A Small-Molecule Modulator of Metal Homeostasis in Gram-Positive Pathogens

    Staphylococcus aureus is a leading agent of antibiotic-resistant bacterial infections in the world. S. aureus tightly controls metal homeostasis during infection, and disruption of metal uptake systems impairs staphylococcal virulence. We identified small molecules that interfere with metal handling...

    Lillian J. Juttukonda, William N. Beavers, Daisy Unsihuay, Kwangho Kim, Gleb Pishchany, Kyle J. Horning, Andy Weiss, Hassan Al-Tameemi, Jeffrey M. Boyd, Gary A. Sulikowski, Aaron B. Bowman, Eric P. Skaar
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