antibodies
Research Article | Therapeutics and PreventionFcγ Receptors Contribute to the Antiviral Properties of Influenza Virus Neuraminidase-Specific AntibodiesThere is a pressing need for next-generation influenza vaccine strategies that are better able to manage antigenic drift and the cocirculation of multiple drift variants and that consistently improve vaccine effectiveness. Influenza virus NA is a key target antigen as a component of a next-generation vaccine in the influenza field, with evidence for a role in protective immunity in humans. However, mechanisms of protection provided by...
Letter to the Editor | Host-Microbe BiologyFurther Mechanisms and Locations in Which Antisporozoite Antibodies Neutralize Malaria Sporozoites
Research Article | Clinical Science and EpidemiologyAntibodies to Enteroviruses in Cerebrospinal Fluid of Patients with Acute Flaccid MyelitisThe presence in cerebrospinal fluid of antibodies to EV peptides at higher levels than non-AFM controls supports the plausibility of a link between EV infection and AFM that warrants further investigation and has the potential to lead to strategies for diagnosis and prevention of disease.
Research Article | Host-Microbe BiologyAntibody-Mediated Protection against Plasmodium Sporozoites Begins at the Dermal Inoculation SiteStudies in experimental animal models and humans have shown that antibodies against Plasmodium sporozoites abolish parasite infectivity and provide sterile immunity. While it is well documented that these antibodies can be induced after immunization with attenuated parasites or subunit vaccines, the mechanisms by and location in which they neutralize parasites have...