TABLE 1 

Pairwise amino acid sequence identity of subunit 1 of spike protein of 2c CoVs

Accession no. and/or isolate% identity for subunit 1 (% identity for receptor binding domain)
NeoCoVPDF-2180EriCoV/2012/174EriCoV/2012/216BtCoV/133HKU4HKU5-1HKU5-5SC2013EMC-2012Al-Hasa1NRC-HKU205
KC869678 , NeoCoV
Predict/PDF-218091.0 (93.1)
KC545383 , EriCoV/2012/17454.7 (59.7)54.3 (60.4)
KC545386 , EriCoV/2012/21654.9 (59.7)54.4 (60.4)99.9 (100)
DQ648794 , BtCoV/13345.1 (42.5)45.5 (42.5)43.9 (50.0)44.0 (50.0)
EF065505 , BatCoV HKU445.1 (41.8)45.7 (41.8)44.3 (50.0)44.4 (50.0)95.6 (96.2)
EF065509 , BatCoV HKU5-147.8 (46.3)47.7 (47.0)45.8 (53.7)45.9 (53.7)57.7 (63.4)58.4 (63.4)
EF065512 , BatCoV HKU5-547.4 (45.5)47.8 (46.3)44.6 (50.7)44.7 (50.7)56.3 (61.8)56.7 (61.8)90.1 (93.9)
KJ473821 , SC201345.5 (42.5)46.2 (44.0)45.8 (55.2)45.9 (55.2)59.7 (57.5)59.7 (56.7)63.7 (73.9)64.1 (73.1)
KC667074 , EMC-201243.5 (40.3)44.4 (41.0)43.9 (47.8)44.1 (47.8)61.2 (64.9)61.1 (63.4)56.5 (63.4)56.7 (61.1)61.4 (61.2)
KF186567 , Al-Hasa143.5 (40.3)44.4 (41.0)43.9 (47.8)44.1 (47.8)61.4 (65.6)61.2 (64.1)56.5 (63.4)56.7 (61.1)61.4 (61.2)99.9 (99.2)
KJ477102 , NRC-HKU20543.7 (39.6)44.4 (40.3)43.8 (47.0)43.9 (47.0)61.1 (64.9)61.0 (63.4)56.3 (62.6)56.4 (60.3)61.4 (60.4)99.1 (98.5)99.2 (99.2)