Allelic variation during persistent meningococcal carriage

  • a Note that each pair of isolates is of the same sequence type and that carriage spanned between 2 and 6 months.

  • b Isolate number (number allocated to the genome sequence of that isolate in the PubMLST/neisseria database).

  • c Total number of analyzed genes excluding truncated genes (average of 41/genome) and duplicated or multicopy genes (e.g., insertion elements [IS], pilE/pilS, and multigene families).

  • d Gene sequences having one or more nucleotide differences between the two paired isolates.