Minor viral variants in OB- and WT-derived viruses

  • a Average ± SEM number of nonsynonymous and synonymous SNVs for each passage (n = 3 to 8 lung homogenates/passage).

  • b Nucleotide change of TTT→CTT.

  • c Nucleotide change of TTT→TTG.

  • d Total number of mice with ≥5% variants.

  • e Average relative frequency of mutation in samples with mutation.