TABLE 1

SHIV.CH505.375H.dCT-infected rhesus macaques, weeks of challenges to infection, age at infection, sex, time to viral control post-ART, and time to viral rebound post-ATI

Animal
group
Animal
identifier
No. of
challenges to
infection (wk)
Age at
infectiona
SexbPre-ART
controlc,e
Time to
viral
control
post-ART
(wk)f
Viral
rebound
post-ATIc,g
Time to
viral
rebound
post-ATI
(wk)
Postrebound
controlc,d,h
Infant4635715MN1Y3N
4634629FN1Y6Y
4635229FN4Y1N
46359310FYNAdNNANA
46367714MYNAY4Y
46380411FN1Y3N
Adult3947218FN1NNANA
4306815FN1NNANA
4326814FN1Y3N
4236815FN1Y3Y
3995018FN4Y2N
38200110FN1NNANA
  • a Ages are in weeks for infants and years for adults.

  • b M, male; F, female.

  • c N, no; Y, yes.

  • d NA, not applicable.

  • e Pre-ART control, plasma VL of ≤15 copies/ml at ART start (12 wpi).

  • f Viral control post-ART, plasma VL of ≤15 copies/ml after ART start.

  • g Viral rebound, plasma VL of ≥10 times the detection limit of the assay (150 copies of vRNA/ml plasma) post-ART discontinuation.

  • h Postrebound control, plasma VL of ≤15 copies/ml after 8 weeks post-ATI in monkeys showing viral rebound.