TABLE 1

Pearson's correlation ρ for each strain versus MMR strains

Strain(s)DescriptionWhole chromosome (bins 1 to 46)Right replichore (bins 1 to 23)Left replichore (bins 46 to 24)Origin (bins 1 to 13 and 46 to 34)Terminus (bins 14 to 33)
ρPaρPaρPaρPaρPa
CollectivebMMR
CollectiveMMR minus A:T→G:C at
5′NAC3′/3′NTG5′ sites
0.94<0.0010.93<0.0010.96<0.0010.97<0.0010.710.004
PFM421ΔrnhA ΔmutL0.74<0.0010.630.0020.84<0.0010.81<0.0010.470.075
PFM669ΔmutL (AB1157)0.59<0.0010.400.0640.75<0.0010.71<0.0010.450.079
PFM430/431oriC+ oriZ+ ΔmutL (AB1157)0.75<0.0010.71<0.0010.81<0.0010.83<0.0010.460.075
PFM426ΔoriC oriZ+ ΔmutL (AB1157)0.390.0080.210.340.620.0030.400.0440.410.11
PFM533/534ΔseqA ΔmutL0.490.0010.71<0.0010.270.230.530.0060.380.14
PFM5bΔmutL on minimal medium0.500.0010.400.0690.610.0030.570.0030.580.029
PFM343bΔmutS on minimal medium0.180.220.180.410.180.410.210.310.220.38
PFM343bΔmutS on diluted LB0.84<0.0010.84<0.0010.85<0.0010.87<0.0010.710.004
PFM343bΔmutS on supplemented
minimal medium
0.81<0.0010.82<0.0010.81<0.0010.83<0.0010.650.008
PFM342bΔmutS at low temperature0.57<0.0010.600.0030.530.0130.69<0.001−0.020.95
PFM799ΔnrdR ΔmutL0.490.0010.580.0050.390.0800.69<0.001−0.310.24
PFM677Δrep ΔmutL0.480.0010.490.0220.480.0270.620.001−0.120.67
PFM256Δtus ΔmutL0.82<0.0010.79<0.0010.85<0.0010.87<0.0010.700.004
PFM257ΔmatP ΔmutL0.400.0070.600.0040.210.340.70<0.001−0.470.075
PFM422ΔrecA ΔmutL0.71<0.0010.70<0.0010.73<0.0010.85<0.0010.060.84
PFM424ΔrecA ΔmutS0.80<0.0010.78<0.0010.83<0.0010.91<0.0010.440.082
PFM456ΔrecB ΔmutL0.82<0.0010.87<0.0010.79<0.0010.89<0.0010.390.12
PFM118ΔumuDC ΔdinB ΔmutL0.59<0.0010.620.0030.550.0100.610.0010.690.004
PFM120lexA3 ΔsulA ΔmutL0.82<0.0010.82<0.0010.83<0.0010.83<0.0010.800.001
PFM259ΔhupB ΔmutL0.73<0.0010.70<0.0010.77<0.0010.81<0.0010.570.031
PFM258ΔhupA ΔmutL0.490.0010.430.0530.580.0050.67<0.001−0.230.38
PFM317/318Δfis ΔmutL0.51<0.0010.610.0030.420.0600.67<0.001−0.300.25
PFM482Δfis ΔmutS0.490.0010.310.150.620.0030.65<0.001−0.280.27
PFM741Δhns ΔmutL0.81<0.0010.81<0.0010.81<0.0010.88<0.0010.460.075
PFM713Δdps ΔmutL0.80<0.0010.84<0.0010.78<0.0010.89<0.0010.470.075
PFM163cmutD50.76<0.0010.79<0.0010.74<0.0010.82<0.0010.780.001
PFM165/397/399cmutD5 ΔmutL0.64<0.0010.76<0.0010.520.0140.86<0.001−0.460.075
CollectivebWild type0.360.0140.410.0610.310.170.370.0650.510.060
CollectivedBacillus subtilis mutS::Tn100.52<0.0010.630.0030.400.0680.74<0.001−0.520.055
  • a P values were adjusted for multiple comparisons using the Benjamini-Hochberg method (56) with the false-discovery rate set at 25%.

  • b Data are from reference 11.

  • c Data are from reference 10.

  • d Data were combined from four MA experiments performed with DK2140 (NCIB3610 mutS::Tn10), DK2141 (NCIB3610 mutS::Tn10), DK2142 (NCIB3610 mutS::Tn10 ΔcomI), and DK2143 (NCIB3610 mutS::Tn10 ΔcomI). There were no differences in mutation rates or spectra among these strains.