TABLE 2

Pearson's correlation ρ of right versus left replichore for each strain

StrainDescriptionWhole chromosome (bins 1 to 23 and 46 to 24)Origin (bins 1 to 13 and 46 to 34)Terminus (bins 14 to 23 and 33 to 24)
ρPaρPaρPa
CollectivebMMR0.91<0.0010.95<0.0010.660.23
CollectiveMMR minus A:T→G:C at 5′NAC3′/3′NTG5′ sites0.89<0.0010.94<0.0010.420.60
PFM421ΔrnhA ΔmutL0.490.0260.580.0510.240.82
PFM669ΔmutL (AB1157)0.520.0180.640.0260.290.77
PFM430/431oriC+ oriZ+ ΔmutL (AB1157)0.600.0050.800.0030.190.84
PFM426ΔoriC oriZ+ ΔmutL (AB1157)0.280.220.330.31−0.060.91
PFM533/534ΔseqA ΔmutL0.410.0620.530.0790.320.71
PFM5bΔmutL on minimal medium0.270.220.190.530.050.91
PFM343bΔmutS on minimal medium−0.020.930.320.31−0.530.39
PFM343bΔmutS on diluted LB0.87<0.0010.93<0.0010.660.23
PFM343bΔmutS on supplemented minimal medium0.74<0.0010.790.0030.540.39
PFM342bΔmutS at low temperature0.84<0.0010.89<0.0010.730.19
PFM799ΔnrdR ΔmutL0.79<0.0010.780.0030.840.07
PFM677Δrep ΔmutL0.430.0530.580.051−0.160.84
PFM256Δtus ΔmutL0.700.0010.88<0.0010.260.81
PFM257ΔmatP ΔmutL0.450.0420.400.200.720.19
PFM422ΔrecA ΔmutL0.660.0010.810.0030.110.88
PFM424ΔrecA ΔmutS0.640.0020.800.0030.070.91
PFM456ΔrecB ΔmutL0.670.0010.780.0030.030.94
PFM118ΔumuDC ΔdinB ΔmutL0.390.0750.680.018−0.130.87
PFM120lexA3 ΔsulA ΔmutL0.510.0190.570.0550.420.60
PFM259ΔhupB ΔmutL0.640.0020.780.0030.350.65
PFM258ΔhupA ΔmutL0.540.0140.690.0150.150.84
PFM317/318Δfis ΔmutL0.610.0040.670.0190.580.34
PFM482Δfis ΔmutS0.340.130.490.1080.190.84
PFM741Δhns ΔmutL0.81<0.0010.850.0010.600.33
PFM713Δdps ΔmutL0.520.0170.770.004−0.200.84
PFM163cmutD50.75<0.0010.770.0040.520.39
PFM165/397/399cmutD5 ΔmutL0.78<0.0010.88<0.0010.390.62
CollectivebWild type0.170.460.240.450.170.84
CollectivedBacillus subtilis mutS::Tn100.73<0.0010.87<0.0010.370.65
  • a P values were adjusted for multiple comparisons using the Benjamini-Hochberg method (56) with the false-discovery rate set at 25%.

  • b Data are from reference 11.

  • c Data are from reference 10.

  • d Data were combined from four MA experiments performed with DK2140 (NCIB3610 mutS::Tn10), DK2141 (NCIB3610 mutS::Tn10), DK2142 (NCIB3610 mutS::Tn10 ΔcomI), and DK2143 (NCIB3610 mutS::Tn10 ΔcomI). There were no differences in mutation rates or spectra among these strains.