TABLE 1

Genes encoding putative mitochondrial proteinsa

ORF
identifierb
Gene nameNon-Candida
ortholog
No. of CTG clade orthologs predicted byc:
MitoPredTargetPPredotar
19.3818GOA1None888
19.1179NUO3None870
19.5077NUO4None887
19.2819NUE1None655
19.1371COE1None878
19.6566COE2None888
19.6918QCE1None515
19.5607None888
19.94None676
19.411None463
19.265None776
19.527None510
19.679FGR39None888
19.935AGA1None744
19.1287None520
19.1344None887
19.1748None483
19.1873None888
19.2650None888
19.3563None450
19.4553None540
19.4734None674
19.4795None778
19.4895None571
19.6853None555
19.4467NUE2YALI0D21648666
19.2513MNE1MNE1777
19.230PET111PET111655
19.102AEP1AEP1544
  • a Genes whose deletion resulted in failure to grow on glycerol are indicated with boldface characters. Those without an effect are indicated with lightface characters. NUO, NADH:ubiquinone oxidoreductase; NUE, NADH:ubiquinone oxidoreductase expression; COE, cytochrome c oxidase expression; QCE, coenzyme Q:cytochrome c oxidoreductase expression.

  • b Designations represent ORF identifiers according to the Candida Genome Database (http://www.candidagenome.org).

  • c Data represent numbers of CTG clade orthologs predicted to have a mitochondrial localization.