TABLE 1

Challenge participant demographics, clinical results, and preexisting antibody titers

CharacteristicaValue for characteristic
Mean age, yr (range)27 (18–47)
SexMaleFemale
No. of participants (%)44 (53.0)39 (47.0)
RaceAsianBlackWhite
No. of participants (%)5 (6.0)35 (41.7)43 (51.1)
GroupNo MMIDMMID
No. of participants3944
Mean max symptom score (range)1.8 (0–7)5.6 (1–14)
Mean no. of days of symptoms (range)3.6 (0–34)6.8 (2–11)
Mean no. of days of shedding (range)0.15 (0–2)3.7 (1–9)
Pre NAI titers (GMT)258.547.7
Pre HAI titers (GMT)22.44.2
Pre HA stalk titers (mean)66,22730,430
QuartileLower quartile (Q1)Median quartile (Q2)Upper quartile (Q3)
Max symptom score136
No. of days of symptoms357.75
No. of days of shedding014
Pre NAI titers (GMT)80160320
Pre HAI titers (GMT)01080
Pre HA stalk titers (mean)23,605.552,014.582,366.5
  • a max, maximum; Pre, preexisting (baseline).