TABLE 5

Susceptibility of efflux knockouts in Acinetobacter

Acinetobacter species (strain)Efflux
knockout
MIC (mg/liter)Fold
change
SulbactamSulbactam-ETX2514
A. baumannii (ATCC 17978)WT110
ΔadeB10.1258
ΔadeJ10.1258
ΔadeBadeJ10.1258
A. nosocomialis (M2)WT212
ΔadeB212
ΔadeJ20.12516
ΔadeBadeJ20.12516