TABLE 1

Selected BldC ChIP-seq targets and corresponding RNA-seq dataa

min apvGeneProductLogFC
10 h14 h
2.42E−10vnz_18945BldC
3.03E−18vnz_35035EshA−8.15−5.34
vnz_350402-Methylisoborneol synthase−4.89−2.80
vnz_350452-Methylgeranyl diphosphate synthase−6.42−5.19
3.19E−17vnz_16495WblA−4.36−5.53
1.40E−06vnz_27205WhiH−4.22−3.77
1.33E−07vnz_22005BldM−2.67−3.02
5.39E−22vnz_18205SsgA−1.81−0.56
vnz_18200SsgR−2.30−2.32
4.48E−32vnz_04805CvnA4−0.18−2.14
vnz_04800CvnB40.00−2.62
vnz_04795CvnC40.19−2.54
vnz_04790CvnD4−0.10−2.79
3.37E−15vnz_25880CvnA10.01−1.15
vnz_25875CvnB1−0.08−1.52
vnz_25870CvnC1−0.16−2.26
vnz_25865CvnD1−0.10−2.27
1.33E−07vnz_22000WhiD6.892.44
1.33E−15vnz_18620SigF4.423.85
2.52E−07vnz_12110DynA3.102.39
vnz_12105DynB3.182.10
1.23E−12vnz_04885SmeA2.730.14
vnz_04890SffA2.700.34
2.33E−12vnz_05545SsgB2.550.74
4.06E−09vnz_13800SigI2.542.76
1.48E−09vnz_24690Cell division protein FtsW-like2.491.86
vnz_24685Penicillin-binding protein2.142.04
2.50E−15vnz_22740Diguanylate cyclase2.272.01
1.87E−27vnz_28820WhiI1.983.03
1.22E−35vnz_12970Penicillin-binding protein1.871.66
7.74E−05vnz_25950HupS1.861.48
7.17E−25vnz_23255Penicillin-binding protein1.451.48
1.04E−17vnz_15130d-Alanyl-d-alanine carboxypeptidase0.820.71
4.46E−06vnz_13645WhiB0.620.51
  • a Listed are the minimum average P value (min apv) for the ChIP-seq peak, the gene, and the gene product. For each target, the RNA-seq data, showing the relative expression values (logFC) for the ΔbldC mutant compared to the wild type at the 10-h and 14-h time points, are also listed. Significant decreases in relative expression (<−1) are indicated in bold. Significant increases in relative expression (>1) are indicated in italic. Where BldC binding is likely to exert control over multiple genes in a single operon, the data for those genes are also listed.