TABLE 2

BacCapSeq yields higher read counts and genome coverage than UHTS in whole blood spiked with bacterial cells

SpeciesGenome
length (nt)
Coding
region (%)
Load
(copies/ml)
Bacterial read countaFold
increase
Genome coverage (%)
BacCapSeqUHTSBacCapSeqUHTS
Bordetella pertussis4,386,3968940,00090,597136694829
4,00014,85816979395
4001,6222725131
40269150880
Klebsiella pneumoniae5,333,9428940,000148,203455339926
4,00016,92940442581
4002,7715551180
405220NAb50
Mycobacterium tuberculosis4,411,5329140,0005,80125243460
4,000845328790
400140NA00
4060NA00
Neisseria meningitidis2,272,3608640,00060,480115546906
4,0006,8948908570
4001,45411,561230
401510NA60
Streptococcus pneumoniae2,038,6158640,0003,0706506430
4,0005881948130
400350NA10
4040NA00
  • a Bacterial reads per 1 million reads are shown without applying a cutoff threshold.

  • b NA, not applicable because fold increase was not calculated for results with <1 read.