TABLE 2

Activities of AX-35 and AX-36 against selected microorganisms

MicroorganismMIC (µg/ml) of:
AX-35AX-36RIF
Bacillus subtilis>100>1000.3
Candida albicans>100>1001.5
Corynebacterium diphtheriae>100>1000.0004
Corynebacterium glutamicum>100>1000.004
Enterococcus faecalis>100>1000.6
Escherichia coli741006.7
Listeria monocytogenes>100>1000.8
Micrococcus luteus>100>1000.7
Mycobacterium avium8.212.825
Mycobacterium bovis BCG0.80.80.0008
Mycobacterium canettii STB-L0.0030.010.002
Mycobacterium marinum11.519.60.5
Mycobacterium massiliense7.710.426.9
Mycobacterium smegmatis100631.7
Mycobacterium tuberculosis0.050.10.001
Mycobacterium ulcerans1.61.60.01
Mycobacterium vaccae12.126.92.5
Pseudomonas aeruginosa>100>1001
Pseudomonas putida>100>1000.2
Salmonella enterica serovar Typhimurium>100>1000.7
Staphylococcus aureus>100>1003.8