TABLE 3 

Production of xanthocillin derivatives in solid plate culture (compounds 7 to 12), comparing the OE::xanC mutant strain to the ΔxanC deletion strain

CompoundProduction of derivative ina:
WTOE::xanC mutantΔxanC deletion mutant
+Cu−Cu+Cu−Cu+Cu−Cu
76.6E7 ± 2.4E71.9E8 ± 4.1E71.6E9 ± 3.1E89.9E8 ± 5.7E800
82.3E7 ± 1.0E76.4E8 ± 2.2E83.8E9 ± 8.1E88.2E9 ± 1.7E900
92.8E5 ± 1.9E59.1E6 ± 6.2E61.3E7 ± 4.9E63.8E8 ± 2.5E801.1E5 ± 6.9E4
103.7E7 ± 8.2E64.8E7 ± 1.1E74.0E8 ± 2.4E85.9E8 ± 3.1E800
115.9E9 ± 7.3E86.4E9 ± 1.2E91.2E10 ± 2.3E96.3E8 ± 1.1E800
122.8E8 ± 4.8E71.6E8 ± 3.5E76.3E8 ± 1.1E83.9E7 ± 4.7E600
  • a The numbers indicate the average ± standard deviation for the peak intensity of each compound determined by LC-HRMS with three replicates.