TABLE 2 

MICs of first-line and second-line TB drugs against the triple auxotrophic strainsa

StrainMIC (mg/liter) of TB drug
First lineSecond line
INHRIFOFKmMoxiETHCFZAmi
mc279010.060.060.520.1250.6250.50.5
mc282511>40.540.1250.6250.50.5
mc282551>40.520.1250.6250.250.5
mc279020.060.060.520.1250.6250.250.5
mc28248>4>40.520.1250.6250.250.5
mc28250>4>40.540.1250.6250.250.5
mc28256>4>40.520.1250.6250.250.5
mc28257>4>40.520.1250.6250.250.5
mc28258>4>40.520.1250.6250.250.5
mc28259>4>40.520.1250.6250.250.5
  • a Abbreviations: Ami, amikacin; CFZ, clofazimine; ETH, ethionamide; INH, isoniazid; Km, kanamycin; Moxi, moxifloxacin; OF, ofloxacin; RIF, rifampin.