TABLE 3 

Genes deleted from mc28245 and mc28250

GeneCoordinatesClaProduct
Rv18672115764–21172481Conserved hypothetical protein
Rv18682117347–211944610Conserved hypothetical protein
Rv1869c2119460–21206957Probable reductase
Rv1870c2120795–212143010Conserved hypothetical protein
Rv1871c2121495–212188410Conserved hypothetical protein
lldD22121907–21231517Possible l-lactate dehydrogenase (cytochrome)
Rv18732123174–212361110Conserved hypothetical protein
Rv18742123684–212437010Hypothetical protein
Rv18752124381–212482410Conserved hypothetical protein
bfrA2125340–21258197Probable bacterioferritin
Rv18772125904–21279673Probable conserved integral membrane protein
glnA32128022–21293747Probable glutamine synthetase
Rv18792129377–213051310Conserved hypothetical protein
cyp1402130541–21318577Probable cytochrome P450 140
lppE2131907–21323293Possible conserved lipoprotein
Rv1882c2132370–21332037Probable short-chain-type dehydrogenase
Rv1883c2133231–213369210Conserved hypothetical protein
rpfC2133731–21342613Probable resuscitation-promoting factor
Rv1885c2134273–21348727Conserved hypothetical protein
fbpB2134890–21358671Secreted antigen 85-B
Rv18872136258–213740010Hypothetical protein
Rv1888c2137519–213807910Possible transmembrane protein
Rv1888A2138444–21386173Conserved hypothetical protein
Rv1889c2138661–213901710Conserved hypothetical protein
Rv1890c2139076–213968710Hypothetical protein
Rv18912139741–214014810Conserved hypothetical protein
Rv18922140165–21404763Probable membrane proteins
Rv18932140486–214070410Conserved hypothetical protein
Rv1894c2140739–214186910Conserved hypothetical protein
Rv18952142521–21436757Possible dehydrogenase
Rv1896c2143535–214444610Conserved hypothetical protein
Rv1897c2144451–214488210Conserved hypothetical protein
Rv18982144940–214524810Conserved hypothetical protein
lppD2145214–21462453Possible lipoprotein
lipJ2146245–21476337Probable lignin peroxidase
cinA2147662–21489540Probable CinA-like protein
nanT2149006–21502743Probable sialic acid transport membrane proteins
Rv19032150364–21507683Probable conserved membrane proteins
Rv19042150954–215138510Conserved hypothetical protein
aao2151433–21523957Probable d-amino acid oxidase
Rv1906c2152425–215289510Conserved hypothetical protein
Rv1907c2153235–215388210Hypothetical protein
katG2153889–21561110Catalase-peroxidase-peroxynitritase T
furA2156149–21566019Ferric uptake regulation protein
Rv1910c2156706–21572993Probable exported protein
lppC2157382–21579873Probable lipoprotein
fadB52158087–21590911Possible oxidoreductase
Rv19132159191–215994310Conserved hypothetical protein
Rv1914c2159921–216032810Hypothetical protein
aceAa2160463–21615667Probable isocitrate lyase (first part)
aceAb2161566–21627627Probable isocitrate lyase (second part)
PPE342162932–21673116PPE family protein
PPE352167649–21706126PPE family protein
  • a Cl, classification, based on the TubercuList website (http://genolist.pasteur.fr/TubercuList/), with the following categories: 0, virulence, detoxification, adaptation; 1, lipid metabolism; 3, cell wall and cell processes; 6, PE/PPE; 7, intermediary metabolism and respiration; 9, regulatory proteins; 10, conserved hypothetical proteins.