TABLE 1 

Summary of obesity, demographic, sequencing, and beta diversity analysis data for the studies used in the meta-analysis

Study (reference)No. of subjects% ObeseAvg BMI (range)% FemaleAvg age in yr (range)% Nonhispanic whiteSequencing
method
16S rRNA
gene region(s)
AMOVA
P value
Baxter (23)17227.327.0 (17.5–46.9)64.554.3 (29.0–80.0)87.8MiSeqV40.078
Escobar (16)3033.327.4 (19.5–37.6)46.738.1 (21.0–60.0)NAa454V20.047
Goodrich (19)98219.726.3 (16.2–52.4)98.961.0 (23.0–86.0)NAMiSeqV4<0.001
HMP (21)28710.824.3 (19.0–34.0)49.126.3 (18.0–40.0)81.5454V3–V50.322
Ross (18)6360.331.6 (22.1–47.9)76.257.0 (33.0–81.0)0.0454V1–V30.845
Schubert (22)10432.728.2 (18.5––62.5)66.352.8 (19.0–88.0)82.7454V3–V50.180
Turnbaugh (10)14667.8NANANA51.4454V20.040
Wu (20)647.824.3 (14.0–41.3)53.126.3 (2.16–50.0)NA454V1, V20.577
Zeevi (17)73121.626.4 (16.4–47.0)NA43.4 (18.0–70.0)NAMiSeqV3, V40.135
Zupancic (15)20736.228.2 (18.2–127.0)57.046.7 (20.0–79.0)100.0454V3–V50.206
  • a NA indicates that those metadata were not available for that study.