TABLE 1 

Comparison of results obtained via culturing and those from the PID assay

Sample IDBlood culture resultPID assay result (peak signal ΔS)ConcordancePCR/sequencing resulta
001E. coliE. coli (197)Yes
005Coagulase-negative staphylococciS. epidermidis groupb (37)YesS. epidermidis
009S. aureusS. aureus (391)Yes
010E. faecalisE. faecalis (506)Yes
012NegativeS. epidermidis group (174)NoS. hominis
015S. aureusS. aureus (13,042)Yes
017Coagulase-negative staphylococciS. epidermidis group (55)YesS. lugdunensis
021Coagulase-negative staphylococciS. epidermidis group (1,518)YesS. epidermidis
023E. coliE. coli (2,567)Yes
024K. oxytocaKlebsiella/Enterobacter (145)Yes
026Coagulase-negative staphylococciNegativeNoNegative
027E. clocaeKlebsiella/Enterobacter (26)Yes
030Viridans groupNegativeYes
031Coagulase-negative staphylococciS. epidermidis group (66)YesS. epidermidis
032NegativeS. epidermidis group (110)NoS. epidermidis
035E. coliE. coli (5,396)Yes
037NegativeS. aureus (4,765)NoS. aureus
039S. aureusS. aureus (110)Yes
040S. aureusS. aureus (53)Yes
043Coagulase-negative staphylococciS. epidermidis group (11,660)YesS. epidermidis
045Viridans groupNegativeYes
046S. aureusS. aureus (12,008)Yes
049NegativeS. aureus (8,874)NoS. aureus
051S. aureusS. aureus (9,455)Yes
052Unknown Gram negativeNegativeYes
053Micrococcus spp.NegativeYes
056S. aureusS. aureus (121)Yes
059Coagulase-negative staphylococciS. epidermidis group (61)YesS. epidermidis
060S. pneumoniaeS. pneumoniae (164)Yes
061S. aureusS. aureus (150)Yes
  • a A negative γPNA assay result indicates that no panel pathogen was present but does not rule out the presence of other, less prevalent pathogens.

  • b The “S. epidermidis group” includes a large number of coagulase-negative staphylococci, such as but not limited to S. epidermidis, S. hominis, S. lugdunensis, and S. haemolyticus.