TABLE 2 

Genes negatively regulated 6 h postinfection

LocusGene nameFold changeFunction
UTI89_C0970ycaC−2.046942047Isochorismatase
UTI89_C3263ygfK−2.056558996Putative selenate reductase subunit YgfK
UTI89_C2911−2.075577539Hypothetical protein
UTI89_C5059−2.102592326Hypothetical protein with predicted transporter domains
UTI89_C2208−2.113388903Hypothetical protein with predicted beta-lactamase domain
UTI89_C2246−2.166165631Putative phosphotriesterase-related protein
UTI89_C3418hybA−2.218168479Hydrogenase 2: Fe-S ferredoxin-type component; participates in the periplasmic electron-transferring activity of hydrogenase 2
UTI89_C4757yieN−2.240676727Hypothetical protein
UTI89_C4841nrdG−2.3253116Anaerobic ribonucleotide reductase-activating protein: activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions
UTI89_C4908−2.330016629Hypothetical protein with DoxX domain
UTI89_C2574yfbS−2.437463493Putative transport protein
UTI89_C3479ygiL−2.451883269Putative fimbrial component
UTI89_C3769−2.463458955Hypothetical protein
UTI89_C4235yidE−2.519812232Putative transporter
UTI89_C1554−2.529382149Hypothetical protein
UTI89_C1183yceO−2.627212273Hypothetical protein
UTI89_C3868−2.645149216Hypothetical protein
UTI89_C2154−2.759997253Hypothetical protein
UTI89_P026−2.890429712Microcin immunity protein
UTI89_C3966−2.915524643Hypothetical protein
UTI89_C4571yjaB−2.959889227Hypothetical protein with N-acyltransferase domain
UTI89_C4147cysE−2.999317444Serine acetyltransferase: cysteine biosynthesis
UTI89_C0224rrfH−3.226337436SS rRNAa
UTI89_C3901−3.240851237Hypothetical protein
UTI89_C4015yhiP−3.672725553Inner membrane transporter member of the POT family of peptide transporters; probable proton-dependent peptide transporter function
UTI89_C3759−4.033641779Hypothetical protein
UTI89_C3283−4.709429327Hypothetical protein
UTI89_C4738fxsA−5.055351Plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein
UTI89_C4261tnaB−6.793467107Tryptophan permease TnaB
UTI89_C0760−7.142857143Hypothetical protein
  • a SS, single stranded.