TABLE 4 

Periprosthetic tissue culture results in subjects meeting Infectious Diseases Society of America criteria for prosthetic joint infection for different culture media

MicroorganismTotal no. (%) of culture-positive PJI (n = 93)No. of culture-positive PJI with the indicated result in periprosthetic tissue culture medium
Blood culture bottleAgarThioglycolate broth
≥1 specimen positive≥2 specimens positive≥1 specimen positive≥2 specimens positive≥1 specimen positive≥2 specimens positive
Staphylococcus species46 (49)444138253622
    S. aureus22 (24)222218141813
    S. epidermidis19 (20)1815179149
    S. lugdunensis2 (2)221120
    S. capitis1 (1)110010
    S. hominis1 (1)001100
    S. saccharolyticus1 (1)111010
Streptococcus species4 (4)433120
    S. agalactiae1 (1)111100
    S. bovis1 (1)111010
    S. gordonii1 (1)111010
    Streptococcus group G1 (1)100000
Enterococcus faecalis2 (2)210011
Other Gram-positive cocci6 (6)444231
    Facklamia hominis1 (1)111011
    Finegoldia magna1 (1)111010
    Granulicatella adiacens2 (2)220000
    Parvimonas micra2 (2)002210
Gram-positive bacilli12 (13)101084118
    Propionibacterium acnes10 (11)8863107
    Propionibacterium granulosum1 (1)111000
    Corynebacterium amycolatum1 (1)111111
Gram-negative bacilli7 (8)777564
    Escherichia coli1 (1)111111
    Proteus mirabilis1 (1)111000
    Enterobacter cloacae1 (1)111111
    Serratia marcescens1 (1)111111
    Pseudomonas aeruginosa2 (2)222120
    Stenotrophomonas maltophila1 (1)111111
Candida albicans1 (1)111111
Polymicrobial5 (5)544454
    S. aureus + P. acnes1 (1)101111
    S. aureus, S. agalactiae, Enterobacter aerogenes, and Gram-positive bacillus1 (1)111111
    S. epidermidis + P. acnes1 (1)110010
    S. epidermidis + E. faecalis1 (1)111111
    Streptococcus sanguis, Haemophilusparainfluenzae, and Veillonella species1 (1)111111
Indeterminate (single positive periprosthetic tissue culture)a10 (11)732000
    S. aureus2 (2)200000
    S. epidermidis1 (1)100000
    S. epidermidis + S. capitis1 (1)101000
    Staphylococcus warneri1 (1)100000
    S. hominis + Gram-positive bacillus1 (1)100000
    Corynebacterium jeikeium1 (1)010000
    Corynebacterium striatum1 (1)010000
    C. amycolatum + Cellulosimicrobium cellulans1 (1)101000
    P. acnes1 (1)010000
  • a Excludes cases with indeterminate culture results in addition to the isolation of a different microorganism isolated from two or more periprosthetic tissue specimens.