TABLE 1 

Modified diffocin Av-CD291.2 prevents colonization in mice exposed to spores from C. difficile isolate BI/NAP1/027

CohortResults fora:
Day 4Day 7b
Infected (n)Total (n)%Infected (n)Total (n)%
Placebo
    Female810801010100
    Male10101001010100
    Total1820902020100
Av-CD291.2
    Female0*100*91090
    Male0**100**1010100
    Total0**200**192095
  • a Asterisks indicate statistically significant difference compared to the placebo control cohort by one-sided Fisher's exact test: *, P < 0.001; **, P < 0.0001.

  • b Three days after termination of treatment.