TABLE 4 

Temperature dependence of neutralization mediated by human MAbs to DENV FLa

MAb% neutralization mediated by MAb
against indicated strain, at 37 or 40°C
DENV2 (strain NGC)DENV4 (strain 1036)
37°C37°C40°C
1C18582968
1B19803890
1C19933043
1E4864687
1F12.2784495
1H20352548
1I169757100
1I17323781
1K16252664
1L4684258
1L6865796
1M12.202461
1M4776197
1M6.2905599
1M7938599
1N5855297
1N8654389
2A15383377
2C7885493
2I238616
2J21443274
2M11764185
3B4866093
3D18864490
3G5624171
3H4907899
4E8723977
5C8735482
5K17864284
5M22112640
  • a Neutralization assays were performed at 2 µg/ml (single endpoint dilution). Data are expressed as % neutralization (i.e., 100% = complete neutralization). These data are from two independent experiments, each performed in duplicate.