TABLE 3 

Prevalences and changes in prevalence of the 40 most common coronal sulcus bacteria for uncircumcised and circumcised men at year 1

Bacterial groupOxygen toleranceaPrevalence (%)bΔΔPrevalence (%)c
UncircumcisedCircumcised
Peptoniphilus spp.AN71 (92.2)37 (46.8)**−40.41
Anaerococcus spp.AN71 (92.2)59 (74.7)−11.39
Unclassified Clostridiales spp.NA65 (84.4)38 (48.1)**−35.31
Prevotella spp.AN70 (90.9)41 (51.9)**−34.21
Finegoldia spp.AN61 (79.2)38 (48.1)**−30.31
Murdochiella spp.AN51 (66.2)12 (15.2)**−43.94
Porphyromonas spp.AN62 (80.5)23 (29.1)**−43.10
Corynebacterium spp.FAN71 (92.2)77 (97.5)**13.46
Unclassified Clostridiales family XINA55 (71.4)20 (25.3)**−43.07
Dialister spp.AN47 (61.0)13 (16.5)**−30.18
Negativicoccus spp.AN35 (45.5)8 (10.1)**−28.95
Peptostreptococcus spp.AN32 (41.6)13 (16.5)*−30.41
Mobiluncus spp.AN31 (40.3)8 (10.1)*−13.69
Gardnerella spp.FAN34 (44.2)32 (40.5)7.56
Lactobacillus spp.FAN/AN/MAE32 (41.6)35 (44.3)1.07
Staphylococcus spp.FAN48 (62.3)*69 (87.3)**36.08
Saccharofermentans spp.AN21 (27.3)10 (12.7)−4.83
Streptococcus spp.FAN34 (44.2)28 (35.4)1.00
Actinomyces spp.FAN27 (35.1)8 (10.1)−12.69
Veillonella spp.AN26 (33.8)16 (20.3)2.53
Peptococcus spp.AN14 (18.2)7 (8.9)5.42
Olsenella spp.AN19 (24.7)5 (6.3)−16.42
Arcanobacterium spp.FAN15 (19.5)4 (5.1)−2.27
Howardella spp.AN18 (23.4)5 (6.3)−3.76
Parvimonas spp.AN13 (16.9)12 (15.2)7.73
Atopobium spp.AN18 (23.4)11 (13.9)−6.46
Sneathia spp.AN15 (19.5)9 (11.4)−7.66
Sutterella spp.AN15 (19.5)2 (2.5)*15.26
Moryella spp.AN11 (14.3)4 (5.1)0.10
Peptostreptococcaceae familyNA4 (5.2)1 (1.3)0.26
Treponema spp.AN8 (10.4)4 (5.1)−6.26
Fusobacterium spp.AN17 (22.1)11 (13.9)−14.22
Pyramidobacter spp.AN7 (9.1)3 (3.8)2.73
Facklamia spp.FAN17 (22.1)21 (26.6)9.96
Anaerosphaera spp.AN9 (11.7)7 (8.9)−5.06
Kocuria spp.AE20 (26.0)36 (45.6)**22.46
Megasphaera spp.AN11 (14.3)10 (12.7)1.23
Micrococcus spp.AE22 (28.6)39.248.40
Gemella spp.FAN15 (19.5)13 (16.5)2.37
Ralstonia spp.AE16 (20.8)2 (2.5)−3.90
  • a  AN, strictly anaerobic; AE strictly aerobic; FAN, facultative anaerobic; MAE, microaerophilic; NA, no data.

  • b  **, FDR-adjusted P value < 0.0001 for change in prevalence over time (i.e., ΔPrevalence); *, FDR-adjusted P value < 0.05 for ΔPrevalence.

  • c  ΔΔPrevalence, shown as a percentile, is the change in prevalence seen for the circumcised men over time compared to that for men that remain uncircumcised.