TABLE 1

HAI and neutralizing activity in immune sera of vaccinated mice

VaccineHAIaNeutralization postvaccinationb
PostvaccinationPostchallenge
Gag only81:20
HK68 4G headless HA plus Gag181:20
PR8 4G headless HA plus Gag181:40
PR8 full-length HA plus Gag≥128≥1281:20,480
  • a The fold increase in titer over Gag-only prechallenge serum is shown.

  • b The highest dilution of serum which achieved at least 50% neutralization is shown.