TABLE 3 

Simultaneous requirements of viroporins by SARS-CoV

Virus nameSARS-CoV viroporinViral titer (PFU/ml)
3aE8a
SARS-CoV wt+++(4.0 ± 1.2) × 107
SARS-CoV Δ8a++(5.0 ± 2.1) × 107
SARS-CoV Δ3a++(1.0 ± 1.9) × 107
SARS-CoV ΔE++(1.0 ± 0.8) × 106
SARS-CoV Δ[E, 8a]+(6.6 ± 1.4) × 105
SARS-CoV Δ[3a, 8a]+(2.4 ± 1.1) × 106
SARS-CoV Δ[3a, E]+    <2.0 × 101a
SARS-CoV Δ[3a, E, 8a]    <2.0 × 101a
  • a Data were below the detection threshold.