TABLE 1 

Isopentenol tolerance-enhancing genes

GeneDescriptionMicroarray log2, z scoreIsopentenol production (mg liter−1)aImprovement in titer (%)bReference(s)
soxSDNA-binding transcriptional dual regulator3.51, 2.81838 ± 29028, 42, 43
nrdHGlutaredoxin-like protein2.17, 2.08860 ± 3344
mdlBPredicted multidrug ABC transporter3.75, 2.31931 ± 161225
ibpAHeat shock chaperone4.80, 2.82967 ± 231626, 27
gidBGlucose-inhibited division protein B5.32, 2.64965 ± 11629, 45, 46
fprFerredoxin-NADP reductase2.30, 2.07989 ± 101928
yqhDAlcohol dehydro-genase, NAD(P) dependent2.40, 2.39994 ± 131914, 30, 31
metRDNA-binding transcriptional activator2.57, 2.551,290 ± 205532, 33
  • a Averages from triplicates after 48 h.

  • b Percent improvement in titer is in comparison to result for PS+RFP at 48 h (834 ± 5 mg liter−1).