TABLE 1 

Transposition frequency of pRM762 and derivatives

PlasmidIS26TargetTransposition frequencya
MeanNo.bRange
pRMH762IS26R3882.9 × 10−6101.3 × 10−6–5.1 × 10−6
pRMH962IS26-FS-LcR388<1.9 × 10−83<2.9 × 10−9– <5.4 × 10−8
pRMH762IS26R388::IS261.8 × 10−4105.4 × 10−5–4.7 × 10−4
pRMH962IS26-FS-LR388::IS265.9 × 10−635.8 × 10−6–7.5 × 10−6
pRMH762IS26R388::IS26-FS–Rd4.3 × 10−633.9 × 10−6–4.9 × 10−6
pRMH962IS26-FS-LR388::IS26-FS–R<3.5 × 10−93<2.4 × 10−9– <5.1 × 10−9
  • a Transposition frequency expressed as cointegrates per transconjugant.

  • b Number of independent determinations.

  • c IS26-FS-L, frameshift mutation in pRMH762 IS26 tnp26.

  • d IS26-FS–R, frameshift mutation in R388::IS26 tnp26.