TABLE 2 

Intestinal concentrations of SCFA in SIHUMI, SIHUMIw/oCra, or Cra mice after 4 weeks of high-fat diet feeding

SCFASCFA concn (µmol/g) ina:
CecumColon
SIHUMIw/oCraSIHUMICraSIHUMIw/oCraSIHUMICra
Acetic acid10.3 ± 0.715.8 ± 1.9*7.6 ± 0.8*10.9 ± 0.816.2 ± 2.57.1 ± 1.2*
Propionic acid 1.7 ± 0.2 2.8 ± 0.50.1 ± 0.0*** 1.2 ± 0.2 1.5 ± 0.20.1 ± 0.0***
Butyric acid 0.4 ± 0.0 0.6 ± 0.1ND 0.2 ± 0.1 0.2 ± 0.1ND
  • a Values are means ± SEM (n = 8 to 9). ND, not detected. *, P < 0.05, and ***, P < 0.001, for obese SIHUMI or Cra mice versus less obese SIHUMIw/oCra mice (reference).