TABLE 1 

Biometric parameters of SIHUMI, SIHUMIw/oCra, or Cra mice, all fed an HFD for 4 weeks

ParameteraResult for miceb
SIHUMIw/oCraSIHUMICra
Body wt (g)
    Wk 027.79 ± 0.5527.11 ± 0.62 (0.469)28.18 ± 0.49 (0.613)
    Wk 429.12 ± 0.4132.43 ± 0.86 (0.003)31.83 ± 0.75 (0.005)
Wt gain (g [wk 4]) 1.33 ± 0.40 5.31 ± 0.95 (0.001) 3.65 ± 0.70 (0.009)
eWAT (mg/g body wt)18.46 ± 2.4728.31 ± 4.23 (0.056)32.49 ± 3.74 (0.006)
mWAT (mg/g body wt)11.81 ± 0.5616.76 ± 1.40 (0.004)15.66 ± 1.36 (0.015)
sWAT (mg/g body wt) 9.69 ± 1.2114.15 ± 1.78 (0.048)12.87 ± 0.84 (0.052)
Energy intake (kJ/day)81.20 ± 2.0387.22 ± 6.99 (0.743)75.25 ± 2.55 (0.085)
Food efficiency (mg/kJ)c 0.57 ± 0.17 2.26 ± 0.40 (0.001) 1.77 ± 0.37 (0.008)
Digestibility of HFD (%)92.57 ± 0.4392.27 ± 0.56 (0.681)92.60 ± 0.64 (0.963)
Digestible energy (kJ/day [wk 3])72.25 ± 6.7670.17 ± 3.97 (0.607)68.63 ± 5.37 (1.000)
  • a eWAT, epididymal white adipose tissue; mWAT, mesenteric white adipose tissue; sWAT, subcutaneous white adipose tissue.

  • b Values are means ± SEM (n = 7 to 9). P values for obese SIHUMI or Cra mice versus less obese SIHUMIw/oCra mice (reference) are shown in parentheses.

  • c Calculated from body weight gain (mg) per consumed energy (kJ) after 4 weeks of HFD feeding.