TABLE 3 

Viral homologues and shared 16S rRNA OTUs within and between subject groups

Site and/or status% Homology in viromeP valueb% Homology in 16S rRNAP valueb
Within groupaBetween groupsaWithin groupaBetween groupsa
Sites
    Saliva7.81 ± 12.035.07 ± 7.780.258447.50 ± 34.1711.58 ± 25.040.1671
    Subgingival plaque37.53 ± 8.9810.60 ± 8.700.012273.01 ± 16.9640.76 ± 35.830.2201
    Supragingival plaque34.45 ± 6.9910.50 ± 8.620.008774.29 ± 16.4340.30 ± 36.160.2143
Health status
    Saliva
        Healthy7.06 ± 9.671.06 ± 2.680.109034.08 ± 37.8236.01 ± 32.960.3416
        Periodontal disease12.43 ± 12.401.07 ± 2.610.125470.11 ± 12.7434.02 ± 32.820.1464
    Subgingival plaque
        Healthy38.63 ± 6.4013.56 ± 5.64<0.000173.41 ± 15.3971.15 ± 15.830.4382
        Periodontal disease37.16 ± 10.8613.59 ± 5.810.022177.23 ± 11.9370.67 ± 15.020.3474
    Supragingival plaque
        Healthy31.25 ± 5.9112.18 ± 4.110.000962.27 ± 34.5065.23 ± 27.160.3862
        Periodontal disease34.66 ± 5.6412.11 ± 4.050.001874.20 ± 13.2664.44 ± 27.660.4181
  • a Based on the mean of 10,000 iterations. One thousand random contigs were sampled per iteration.

  • b Empirical P value based on the fraction of times the estimated percent homologous contigs or shared OTUs for each group exceeded that between groups. Values that indicate statistical significance are in bold.