TABLE 1 

Immunologic, virologic, and genotypic characteristics of NP and PR

Subject or parameterInfection duration (yr)aMean no. of CD4+ T cells ± SEbMean HIV-1 load ± SEcHLA class I genotypeCCR5Δ32d
NP1>101,007 ± 31571 ± 9015:01/42:01WT/WT
NP2>251,259 ± 624,764 ± 4,43214:02/47:01WT/WT
NP3>8924 ± 623,055 ± 56639:10/53:01WT/WT
NP4>8743 ± 593,242 ± 1,93135:01/81:01WT/WT
NP5>8622 ± 2967,006 ± 26,52835:01/41:02WT/WT
NP6>12541 ± 311,014 ± 13215:10/42:01WT/WT
NP719.5759 ± 5720,893 ± 7,58515:01/44:02WT/WT
NP816.5783 ± 2750,105 ± 23,96818:01/51:01WT/Δ32
 Mean ± SEe878 ± 3015,871 ± 3,980
PR16.5204 ± 30429,049 ± 91,57808:01/35:03WT/WT
PR28.5443 ± 2859,065 ± 12,83540:01/44:02WT/WT
PR32.9308 ± 5163,159 ± 36,95837:01/06:02WT/WT
PR4f>5350 ± 57147,660 ± 65,97438:01/49:01WT/WT
PR5f2.1232 ± 49396,572 ± 136,55250:01/57:01WT/WT
PR6f3.8245 ± 125188,576 ± 45,18708:01/51:01WT/WT
PR75.2362 ± 6540,604 ± 12,23413:02/35:01WT/WT
PR86.1374 ± 28117,151 ± 28,05908:01/35:01WT/WT
 Mean ± SEe391 ± 21212,956 ± 32,621
  • a Years of HIV-1 infection prior to ART, death, or discontinuation in the MACS.

  • b Number of cells/mm3.

  • c Number of HIV-1 RNA copies/ml of plasma.

  • d WT, wild type.

  • e Mean ± SE CD4+ T cell counts and viral loads were determined at approximately 6-month intervals over the indicated numbers of years of infection.

  • f Deceased.