Common and unique nonribosomal peptide synthase (NRPS) and polyketide synthase (PKS) gene clusters in dermatophytes

Type of clusterTotal no.
of clusters
No. of clusters common
to four or more
No. of clusters unique to less than three dermatophytes
T. rubrumT. tonsuransT. equinumA. benhamiaeT. verrucosumM. canisM. gypseum
Nonreducing PKS830110040
Reducing PKS1350111146
Reducing PKS/NRPS hybrids830000032
Species totals, including commonb432323222325243227
  • a  In these clusters, some of the genes in a given species may be missing because of gaps in the sequence.

  • b Total numbers within a species include those clusters in common as well as those that are unique. See Table S3 in the supplemental material for all details. For a comparison, C. immitis has 16 total clusters (5).