TABLE 1

Virus titers in the lungs of genetically diverse mouse strains inoculated with A/Hong Kong/213/03 H5N1 virus

Mouse strainVirus titera (log10 TCID50/ml)Viral burdenb (AUC)
Day 2Day 4Day 7
DBA/2S6.55.74.834.6
129/SvImS5.95.14.631.4
A/JS5.85.04.030.0
SMR4.94.63.226.1
C57BL/6R4.95.03.627.8
BALB/cR5.64.62.225.9
  • a  Lung virus titers (50% tissue culture infectious doses [TCID50s]) at days 2, 4, and 7 after inoculation with 104 EID50 of A/Hong Kong/213/03 influenza virus are shown.

  • b  Area under the curve (AUC) for influenza virus titers between days 0 and 7 after inoculation with 104 EID50 of A/Hong Kong/213/03 influenza virus are shown.