Comparison of in vitro and in vivo nonlytic exocytosis rates

ConditionNo. of macrophagesaNo. nonlytic exocytosis%P valueb
In vitro 52,8795,0499.55
In vivo 52023344.83<0.0001
  • a  C. neoformans-containing BMM were intratracheally injected into mice and collected 24 h later for nonlytic exocytosis measurements by flow cytometry. Results from two independent experiments performed on different days were pooled.

  • b  P values were calculated using the chi-square test with Yates correction.