TABLE 2 

Estimated PCV7-associated reductionsa in the U.S. burden of hospitalizations for various pneumococcal pneumonia outcomes, 1999–2000 through 2005–2006 seasons

Age groupEstimated IPD reduction95% CIEstimated pneumococcal (lobar) pneumonia (ICD9 481) reduction95% CIEstimated nonbacteremic pneumococcal pneumonia (ICD9 481 with no IPD codes) reduction95% CIEstimated attributed (model-derived) pneumococcal pneumonia reduction95% CIEstimated all-cause pneumonia reduction95% CI
<28,4408,101–8,7524,4373,550–5,2163,3994,119–2,57236,44231,928–40,66780,49456,295–103,022
2–42,0251,766–2,2441,442741–2,0679341,590–1882,5402,156–2,899−3,920−16,325–7,818
5–171,5281,257–1,7724,5443,863–5,1703,9774,595–3,30538,21135,064–41,1878,879368–17,121
18–398,5927,658–9,43228,34426,324–30,24921,80823,411–20,09486,92574,592–97,88182,29947,421–113,857
40–647,2705,428–9,00430,53627,469–33,45024,61426,976–22,169122,239104,095–139,195−35,071−71,505–−530
≥6520,04616,851–23,014113,789101,965–124,90599,415110,428–87,565502,482447,571–553,54662,987−50,803–173,014
Total47,89941,060–54,218183,093163,911–201,057154,147171,118–135,893788,838695,406–875,376195,668−34,550–414,303
  • a Cumulative number of cases prevented since vaccine introduction.