TABLE 2

Associations between S. pneumoniae colonization determined by culture and factors obtained by PCA as well as individual taxa within factors

FactorOR (95% CI)b
PCA factorComponent
Factor A0.55 (0.35, 0.86)
Corynebacterium0.99 (0.95, 1.03)
Dolosigranulum0.99 (0.91, 1.06)
Streptococcusa1.06 (1.03, 1.09)
Factor B0.34 (0.20, 0.56)
Lactococcus0.73 (0.61, 0.89)
Propionibacterium0.89 (0.79, 1.00)
 Unclassified Proteobacteria0.94 (0.88, 1.02)
Staphylococcus0.98 (0.93, 1.02)
Factor C0.94 (0.64, 1.39)
 Unclassified Pasteurellaceae1.08 (1.00, 1.16)
Moraxellaa1.03 (0.99, 1.07)
Haemophilus1.02 (0.98, 1.05)
Factor D0.61 (0.37, 1.02)
Veillonella0.98 (0.83, 1.15)
Neisseria0.85 (0.70, 1.04)
Rothia0.82 (0.62, 1.08)
Actinomyces0.77 (0.58, 1.02)
  • a  The OTU was negatively correlated with the factor; factor loadings were otherwise positive.

  • b OR and 95% CI values were obtained by separate logistic regression analyses of each factor and each taxa within each factor.