TABLE 1 

E. coli MCR1_NJ susceptibilities determined by broth microdilution for all antimicrobials utilized in the time-kill experiments and hollow-fiber infection model

Antimicrobial agentMIC (μg/ml)
Amikacin4
Ampicillin-sulbactam>128/64
Aztreonam≤0.25
Cefoxitin>64
Ceftazidime>64
Ceftazidime-avibactam>16/4
Ceftolozane-tazobactam>256/4
Chloramphenicol>64
Ciprofloxacin>64
Meropenem>64
Nitrofurantoin16
Piperacillin-tazobactam128/4
Polymyxin B4
Rifampin>64
Tigecycline0.50
Trimethoprim-sulfamethoxazole2/38