TABLE 1 

MIC profiles of mcr-3-carrying Escherichia coli isolate WJ1, its transconjugant Ec600 + pWJ1, and recipient isolate EC600

DrugbMIC (mg/liter) for E. coli strain:Associated resistance gene(s) in plasmid pWJ1
WJ1EC600EC600 + pWJ1
COL80.54mcr-3
PB80.254mcr-3
CIP1280.06250.25aac(6′)-Ib-cr
CHL5124512floR, cmlA1, catB3
STR64864strA, strB, aadA1, aadA2
GEN5121512aac(3)-IVa
RIF512512a512arr3
AMC32/164/232/16blaOXA-1
SXT>32/6080.5/9.5>32/608sul1, sul2, sul3
TET128164tet(A)
  • a EC600 is a rifampin-resistant strain used for transconjugation.

  • b Abbreviations: COL, colistin; PB, polymyxin; CIP, ciprofloxacin; CHL, chloramphenicol; STR, streptomycin; GEN, gentamicin; RIF, rifampin; AMC, amoxicillin-clavulanic acid; SXT, trimethoprim-sulfamethoxazole; TET, tetracycline.