Influenza Virus Hemagglutinin Stalk-Specific Antibodies in Human Serum are a Surrogate Marker for In Vivo Protection in a Serum Transfer Mouse Challenge Model

DOI: 10.1128/mBio.01463-17

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^a Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA
^b Graduate School of Biological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA
^c Influenza Centre, Department of Clinical Science, University of Bergen, Bergen, Norway
^d Section for Infectious Diseases, Medical Department, Haukeland University Hospital, Bergen, Norway
^e Department of Clinical Science, Broeglemann Research Laboratory, University of Bergen, Bergen, Norway
^f KG Jebsen Centre for Influenza Vaccine Research, Department of Clinical Science, University of Bergen, Bergen, Norway
^g Department of Research and Development, Haukeland University Hospital, Bergen, Norway

Address correspondence to Raffael Nachbagauer, raffael.nachbagauer{at}mssm.edu.
Citation Jacobsen H, Rajendran M, Choi A, Sjursen H, Brokstad KA, Cox RJ, Palese P, Krammer F, Nachbagauer R. 2017. Influenza virus hemagglutinin stalk-specific antibodies in human serum are a surrogate marker for in vivo protection in a serum transfer mouse challenge model. mBio 8:e01463-17. https://doi.org/10.1128/mBio.01463-17 .
↵* Present address: Henning Jacobsen, Heinrich Pette Institute, Leibniz Institute of Experimental Virology, Hamburg, Germany.

This article is a direct contribution from a Fellow of the American Academy of Microbiology.

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