Topoisomerase II Inhibitors Induce DNA Damage-Dependent Interferon Responses Circumventing Ebola Virus Immune Evasion

DOI: 10.1128/mBio.00368-17

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Editors and / or Reviewers

Terence S. Dermody, Editor, University of Pittsburgh School of Medicine
Erich Mackow, Solicited external reviewer, Stony Brook University
Hideki Ebihara, Solicited external reviewer, National Institute of Allergy and Infectious Diseases, NIH

^a Center for Microbial Pathogenesis, Institute for Biomedical Sciences, Georgia State University, Atlanta, Georgia, USA
^b Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA
^c Department of Pathology, Galveston National Laboratory, The University of Texas Medical Branch at Galveston, Galveston, Texas, USA
^d Department of Biochemistry, UT Southwestern Medical Center, Dallas, Texas, USA
^e Global Health and Emergent Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA
^f Department of Medicine, Division of Infectious Diseases, Icahn School of Medicine at Mount Sinai, New York, New York, USA
^g Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA
^h Department of Microbiology & Immunology, University of Texas Medical Branch at Galveston, Galveston, Texas, USA
ⁱ Galveston National Laboratory, University of Texas Medical Branch at Galveston, Galveston, Texas, USA

Address correspondence to Christopher F. Basler, cbasler{at}gsu.edu.
Citation Luthra P, Aguirre S, Yen BC, Pietzsch CA, Sanchez-Aparicio MT, Tigabu B, Morlock LK, García-Sastre A, Leung DW, Williams NS, Fernandez-Sesma A, Bukreyev A, Basler CF. 2017. Topoisomerase II inhibitors induce DNA damage-dependent interferon responses circumventing Ebola virus immune evasion. mBio 8:e00368-17. https://doi.org/10.1128/mBio.00368-17 .

This article is a direct contribution from a Fellow of the American Academy of Microbiology.

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